Hyperion

3, 4- Divanillyltetrahydrofuran is a natural extract of stinging nettle roots which has been found to have “remarkably high activity” when it comes to inhibiting Sex Hormone Binding Globulin (SHBG). SHBG limits the activity of testosterone and other androgens. SHBG levels increase as we age leading to less free testosterone.

7,8- Dihydroxyflavone is sometimes called “tropoflavin.” This naturally occurring antioxidant has been studied for its ability to mimic the activity of Brain Derived Neurotrophic Factor (BDNF) and activate “tropomyosin receptor kinase B” (TrkB). BDNF production naturally decreases as we age; therefore, BDNF mimetics like 7,8-Dihydroxyflavone have been studied for their potential to help mitigate the symptoms of various age-related conditions as well as many neurological diseases. Additionally, 7,8-Dyhydroxyflavone has been studied for its potential to help balance elevated estrogen levels, at high concentrations.

Dehydroepiandrosterone is the most abundant circulating steroid present in the human body, with production increasing in early teen years and peaking during an individual's mid 20's, and gradually declining as one ages. High levels have been linked to reducing the risk of depression, cardiovascular disease, and it is suggested that dehydroepiandrosterone supplements might overcome age-related decline. High levels of dehydroepiandrosterone have also been linked to reducing the risk of depression, cardiovascular disease, and even death in some studies. In the elderly, DHEA exerts an immunomodulatory action, increasing the number of monocytes, T cells expressing T-cell receptor gamma/delta (TCRγδ) and natural killer (NK) cells. It improves physical and psychological well-being, muscle strength and bone density, and reduces body fat and age-related skin atrophy stimulating procollagen/sebum production.

Vitamin C as ascorbyl palmitate and Vitamin E as mixed tocopherols are vitamins most often used for their antioxidant capacity but there are numerous other benefits as well. Vitamin has been studied as a preventative factor for neuropathy (nerve pain) from various causes including chemotherapy and Type 2 diabetes. A combination of Vitamin E and Vitamin C was studied for its potential to prevent stress-related declines in natural testosterone production. Similar combinations have been shown to protect testosterone-producing cells from various forms of oxidative stress. Vitamin C and Vitamin E have been extensively studied both individually and in combination for their potential to help with several age-related diseases.